Atypical Leber’s Optic Neuropathy

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the spectrum of mitochondrial dna mutations in iranian lebers hereditary optic neuropathy patients

we studied 74 patients with lebers hereditary optic neuropathy (lhon) to investigate causative mtdna mutations (g3460a, g11778a, t14484c, g4459a) in iranian lhon patients. fifty two patients carried the mitochondrial dna (mtdna) g11778a mutation, while one had the t14484c mutation 4 patients had the g3460a mutation and one had the g14459a mutation. our results showed a similarity in the pattern...

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lack of association between lebers hereditary optic neuropathy primary point mutations and multiple sclerosis in iran

the hypothesis that mitochondrial genes may be implicated in susceptibility to multiple sclerosis (ms) is supported by an increasing number of case reports on lebers hereditary optic neuropathy (lhon)-associated mitochondrial dna (mtdna) point mutations in patients with ms. a number of mtdna mutations with primary pathogenic significance for lhon, a maternally inherited disease causing severe b...

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Traumatic ischaemic optic neuropathy.

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[Leber's hereditary optic neuropathy].

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1993

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-7-5-8